Leggenda designs and manufactures automated pre-filled syringe (PFS) filling lines engineered specifically for small-volume liquid injection products in biopharmaceutical and medical aesthetics. Founded in Shanghai in 2019, we deliver everything from standalone fillers to fully integrated turnkey lines - each configured around the customer's product, container format, and production capacity.
80% of our staff are technical professionals, led by a core engineering team with over 10 years of specialized experience in aseptic processing and PFS automation. We have worked across global GMP standards and diverse formulation requirements - from gel crystallization to micro-sphere shear sensitivity. We don't just supply equipment,we provide the technical assurance behind your process.
Today our equipment operates at customer sites across Germany, South Korea, India, Malaysia, Mexico, and more than ten other markets. Our customers include specialized biotech firms, leading medical aesthetics brands, and global medical device manufacturers.
We don't just sell machines; we solve problems. Your production targets become our engineering parameters.
In validation and delivery, promises are commitments. We own the outcome from FAT to SAT and beyond.
Complex lines require seamless integration. We work as an extension of your engineering team.
We innovate for reliability, not complexity. Every feature serves a purpose in your production efficiency.

Providing fully automated customized production lines covering de-nesting → filling & stoppering → inspection → plunger rod insertion & labeling → tray loading/packaging.

Providing bubble-free filling solutions for high-viscosity products such as hyaluronic acid, collagen, microspheres, gels, cross-linked materials, and agarose.

Offering modular designs and fast changeover solutions based on product characteristics and production requirements, compatible with prefilled syringes, cartridges, vials, and other container formats.

Integrating GMP audit requirements and 21 CFR Part 11 data integrity standards into equipment design from the beginning, with audit trail support.

Our 5,000 m2 Shanghai facility combines in-house precision machining, cleanroom-standard assembly, and dedicated Factory Acceptance Test (FAT) bays. Certified to ISO 9001, our quality system covers raw material inspection, in-process checks, and full FAT documentation - ensuring every line meets spec before it ships.
Lead times typically range from 90 to 150 days, depending on project scope and customization level. The result: shorter on-site installation, smoother qualification, and a validated production line running from day one.