Pre-filled Syringe Flushing Filling Production Line-Leggenda (Shanghai) Technology Co., Ltd.

Leggenda provides integrated automated production solutions for pre-filled syringe flushing products, covering syringe loading, precision filling, stoppering, rod screwing, labeling and final tray packing. The system is designed for large-scale manufacturing of normal saline, heparin lock flush solutions and medical gels, ensuring high efficiency, reliable sterility and consistent product quality.

8,000–15,000
syringes/hour Production Capacity
±0.5%
Filling Accuracy
ISO Class 5 (Grade A)
Aseptic Environment
3mL / 5mL / 10mL
Syringe Formats

Workflow

01 Syringe Magazine Loading Station

Store bulk glass syringes and supply stably for subsequent operations
02 Syringe Sorting Station

Align and arrange syringes to ensure orderly feeding into production
03 Syringe Feeding Station

Feed sorted glass syringes continuously into the main production line
04 Ionized Air Cleaning Station

Remove dust and static electricity from syringe inner and outer surfaces
05 Silicone Oil Spraying Station

Spray uniform silicone oil to lubricate inner wall of glass syringes
06 Filling Station

Accurately meter and fill flush liquid into ready glass syringes
07 Syringe Indexing Wheel

Transfer syringes smoothly between different processing stations
08 Syringe Cap Inspection Station

Check whether protective caps are properly fitted on syringes
09 Full Servo Capping Station

Tighten syringe protective caps precisely via full servo control system
10 Cap Feeding Station

Deliver protective caps continuously and orderly to capping station
11 Filling & Dosing Unit

Perform accurate volumetric liquid dosing for flush syringes
12 Stoppering Unit

Insert rubber stoppers into filled syringes under controlled pressure
13 Vision Inspection Unit

Use high-speed camera to detect defects on finished syringes
14 Defect Reject Unit

Automatically pick out non-conforming products after vision inspection

Specification

Category	Specification / Technology
Production Capacity	4/6/8 nozzle configurations, output up to 8,000–15,000 syringes/hour
Filling Accuracy	Servo-driven ceramic pump with ±0.5% filling accuracy
Flexible Production	Supports 3mL, 5mL and 10mL syringe formats with rapid changeover
Aseptic Protection	ISO Class 5 (Grade A) laminar flow protection
Material Compatibility	Supports normal saline, heparin flush solutions and sterile medical gels
Contact Parts	316L stainless steel product-contact components
Compliance & Traceability	cGMP/FDA compliance with electronic batch records and MES integration

FAQ

Q: Can the line be integrated with isolator or RABS systems?

A: Yes. The complete line can be configured with RABS or isolator systems to meet higher aseptic requirements. Cleanliness levels are selectable per your facility's classification needs.
Q: How long does format changeover take on the line?

A: With trained operators, switching between 3/5/10 mL syringe sizes typically takes under 30 minutes. Modular station design minimizes downtime during changeovers.
Q: Can one line handle different viscosity formulations?

A: Yes. Through ceramic pump selection and parameter adjustment, the line accommodates low-viscosity saline through to high-viscosity medical gels. If your formulation has specific viscosity requirements, please leave your contact information and our engineering team will evaluate it for you.

Ready to Optimize Your Filling Line?

Based on your filling materials, container specifications, filling volume per unit, and target production capacity, we will recommend the most suitable production line and optional equipment configurations.

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